Article
Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects.
PLoS genetics - 1 Sept 2012
Yang Xiaobo, Sun Jielin, Gao Yong, Tan Aihua, Zhang Haiying, Hu Yanling, Feng Junjie, Qin Xue, Tao Sha, Chen Zhuo, Kim Seong-Tae, Peng Tao, Liao Ming, Lin Xiaoling, Zhang Zengfeng, Tang Minzhong, Li Li, Mo Linjian, Liang Zhengjia, Shi Deyi, Huang Zhang, Huang Xianghua, Liu Ming, Liu Qian, Zhang Shijun, Trent Jeffrey M, Zheng S Lilly, Xu Jianfeng, Mo Zengnan
Abstract excerpt
Complement C3 and C4 play key roles in the main physiological activities of complement system, and their deficiencies or over-expression are associated with many clinical infectious or immunity diseases. A two-stage genome-wide association study (GWAS) was performed for serum levels of C3 and C4. The first stage was conducted in 1,999 healthy Chinese men, and the second stage was performed in an additional 1,496...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.