Article

Chromatin remodeler <i>Arid1a</i> regulates subplate neuron identity and wiring of cortical connectivity

2020-12-14

Abstract excerpt

Loss-of-function mutations in chromatin remodeler gene ARID1A are a cause of Coffin-Siris syndrome, a developmental disorder characterized by dysgenesis of corpus callosum. Here, we characterize Arid1a function during cortical development and find unexpectedly selective roles for Arid1a in subplate neurons. Subplate neurons (SPNs), strategically positioned at the interface of cortical grey and white matter, orc...

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Literature Corpus work: 947f9b16-b343-5b94-9b38-2753b0243b6a
DOI: 10.1101/2020.12.14.422645

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Chromatin remodeler <i>Arid1a</i> regulates subplate neuron identity and wiring of cortical connectivityDOI 10.1101/2020.12.14.422645Read

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