Article

ARID1B controls transcriptional programs of axon projection in the human corpus callosum

2023-05-04

Abstract excerpt

Mutations in ARID1B , a member of the mSWI/SNF complex, cause severe neurodevelopmental phenotypes with elusive mechanisms in humans. The most common structural abnormality in the brain of ARID1B patients is agenesis of the corpus callosum (ACC). This condition is characterized by a partial or complete absence of the corpus callosum (CC), an interhemispheric white matter tract that connects distant cortical regio...

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Literature Corpus work: 58dfa3d8-0b5e-58ba-a194-14c967beaf03
DOI: 10.1101/2023.05.04.539362

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