Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specification

2 Sept 2024

Abstract excerpt

The BAF chromatin remodeler regulates lineage commitment including cranial neural crest cell (CNCC) specification. Variants in BAF subunits cause Coffin-Siris syndrome (CSS), a congenital disorder characterized by coarse craniofacial features and intellectual disability. Approximately 50% of individuals with CSS harbor variants in one of the mutually exclusive BAF subunits, ARID1A/ARID1B . While Arid1a deletion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39226899
DOI: 10.1016/j.ajhg.2024.07.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specificationPMID 39226899Read ↗

ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial to mesenchymal transition in cranial neural crest lineage commitmentSemantic proximity Read ↗

Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders.Semantic proximity Read ↗

Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in <i>ARID1B</i> -related neurodevelopmental disordersSemantic proximity Read ↗

ARID1B is a Dosage-sensitive Regulator of Polycomb Repressive Complex Distribution and HOX Gene Regulation in Patient-derived Neural ProgenitorsSemantic proximity Read ↗

Abnormal Chromatin Remodeling Caused by ARID1A Deletion Leads to Malformation of the Dentate GyrusSemantic proximity Read ↗

The Evolutionary Conserved SWI/SNF Subunits ARID1A and ARID1B Are Key Modulators of Pluripotency and Cell-Fate DeterminationSemantic proximity Read ↗

ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosumSemantic proximity Read ↗

Hirschsprung disease as a yet undescribed phenotype in a patient with ARID1B mutation.Semantic proximity Read ↗

<i>Eed</i> controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crestSemantic proximity Read ↗

ARID5B mutations cause a neurodevelopmental syndrome with neuroinflammation episodesSemantic proximity Read ↗

Dual role of ZIC2 during neural induction: from pioneer transcription factor to enhancer activatorSemantic proximity Read ↗

Chromatin remodeler <i>Arid1a</i> regulates subplate neuron identity and wiring of cortical connectivitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.