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Evidence that Dmrta2 acts as a transcriptional repressor of <i>Pax6</i> in murine cortical progenitors and identification of a mutation crucial for DNA recognition associated with microcephaly in human

2024-09-20

Abstract excerpt

<h4>ABSTRACT</h4> Dmrta2 (also designated Dmrt5) is a transcriptional regulator expressed in cortical progenitors in a caudomedial high /rostrolateral low gradient with important roles at different steps of cortical development. Dmrta2 has been suggested to act in cortex development mainly by differential suppression of Pax6 and other homeobox transcription factors such as the ventral telencephalic regulator Gs...

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Literature Corpus work
eb400e5c-e74a-57fb-9235-d5cf7dca7b5b
DOI
10.1101/2024.09.20.614077
Open publication

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Evidence that Dmrta2 acts as a transcriptional repressor of <i>Pax6</i> in murine cortical progenitors and identification of a mutation crucial for DNA recognition associated with microcephaly in humanDOI 10.1101/2024.09.20.614077
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