Article

Exploration of Alzheimer’s Disease MRI Biomarkers Using <i>APOE4</i> Carrier Status in the UK Biobank

2021-09-14

Abstract excerpt

Large-scale datasets enable novel strategies to refine and discover relations among biomarkers of disease. Here 30,863 individuals ages 44-82 from the UK Biobank were analyzed to explore MRI biomarkers associated with Alzheimer’s disease (AD) genetic risk as contrast to general effects of aging. Individuals homozygotic for the E4 variant of apolipoprotein E ( APOE4 ) overlapped non-carriers in their 50s but demons...

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Literature Corpus work: 946993dc-53bf-5af5-9f01-51b73ae4277f
DOI: 10.1101/2021.09.09.21263324

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