Article

A comprehensive analysis of <i>APOE</i> genotype effects on human brain structure in the UK Biobank

2023-06-21

Abstract excerpt

Alzheimer’s disease (AD) risk is increased in carriers of the apolipoprotein E ( APOE ) ε4 allele and decreased in ε2 allele carriers compared with the ε3ε3 genotype. The aim of this study was to determine whether: APOE genotype affects brain grey (GM) or white matter (WM) structure; and if differences exist, the age when they become apparent and whether there are differential effects by sex. We used cross-secti...

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Literature Corpus work: cdea9fa3-d30e-5fdf-ab4c-6ff524689dff
DOI: 10.1101/2023.06.19.543571

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