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Article

Effects of ApoE4 and ApoE2 genotypes on subcortical magnetic susceptibility and microstructure in 27,535 participants from the UK Biobank.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2000

Nir Talia M, Zhu Alyssa H, Gari Iyad Ba, Dixon Daniel, Islam Tasfiya, Villalon-Reina Julio E, Medland Sarah E, Thompson Paul M, Jahanshad Neda

Abstract excerpt

Disrupted iron homeostasis is associated with several neurodegenerative diseases, including Alzheimer's disease (AD), and may be partially modulated by genetic risk factors. Here we evaluated whether subcortical iron deposition is associated with ApoE genotype, which substantially affects risk for late-onset AD. We evaluated differences in subcortical quantitative susceptibility mapping (QSM), a type of MRI...

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PMID: 34890142
PMCID: PMC9009383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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