Article

Pioneer activity of an oncogenic fusion transcription factor at inaccessible chromatin

2020-12-12

Abstract excerpt

<h4>Summary</h4> Recent characterizations of pioneer transcription factors have led to new insights into their structures and patterns of chromatin recognition that are instructive for understanding their role in cell fate commitment and transformation. Intersecting with these basic science concepts, the identification of pioneer factors (PFs) fused together as driver translocations in childhood cancers raises qu...

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Literature Corpus work: 9435ccf8-07f6-5dc2-bc86-49aa947f8cda
DOI: 10.1101/2020.12.11.420232

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