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Article

Enhancer plasticity sustains oncogenic transformation and progression of B-Cell Acute Lymphoblastic leukemia

2022-05-19

Abstract excerpt

<h4>ABSTRACT</h4> Growing evidence report that non-genetic-driven events such as enhancer reprogramming promote neoplastic transformation and strongly contribute to the phenotypical heterogeneity of cancers as much as genetic variation. In this context, we investigated the role of enhancers in sustaining oncogenic transformation in B-Cell Acute Lymphoblastic leukemia in children (BCP-ALL), a type of cancer caused...

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Literature Corpus work
49e9fe5f-9c46-550f-835f-e091dc87d3bb
DOI
10.1101/2022.05.18.492497
Open publication

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Enhancer plasticity sustains oncogenic transformation and progression of B-Cell Acute Lymphoblastic leukemiaDOI 10.1101/2022.05.18.492497
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