Article

Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment

2022-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Neoadjuvant chemotherapy (NACT) used for triple negative breast cancer (TNBC) eradicates tumors in approximately 45% of patients. Unfortunately, TNBC patients with substantial residual cancer burden have poor metastasis free and overall survival rates. We previously demonstrated mitochondrial oxidative phosphorylation (OXPHOS) was elevated and was a unique therapeutic dependency of residual TNBC...

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Literature Corpus work: 93f36d0b-5142-5b6a-b3d2-841ea13bc927
DOI: 10.1101/2022.02.25.481996

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