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Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer

5 Jun 2020

Abstract excerpt

BACKGROUND: Mitochondrial dynamics underlies malignant transformation, cancer progression, and response to treatment. Current research presents conflicting evidence for functions of mitochondrial fission and fusion in tumor progression. Here, we investigated how mitochondrial fission and fusion states regulate underlying processes of cancer progression and metastasis in triple-negative breast cancer (TNBC)....

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PMID: 32503622
DOI: 10.1186/s13058-020-01301-x

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