Article

Three-dimensional electron microscopy uncovers mitochondrial network remodeling in residual triple negative breast cancer persisting after conventional chemotherapy treatments

2024-09-09

Abstract excerpt

<h4>ABSTRACT</h4> Mitochondria are hubs of metabolism and signaling, playing crucial roles in tumorigenesis, therapeutic resistance, and metastasis in many types of cancer. Various laboratory models of cancer demonstrate the extraordinary dynamics of mitochondrial structure, but little is known about the full extent of the complexity of the mitochondrial network, nor its regulation upon exposure to therapeutic st...

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Literature Corpus work: 60987406-07fb-54c8-b6cd-504a8731a4cf
DOI: 10.1101/2024.09.09.611245

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