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Targeting DRP1 mediated mitochondrial metabolism as a novel treatment strategy for triple negative breast cancer (TNBC)

2023-04-19

Abstract excerpt

<h4>Background: </h4> Triple-negative breast cancer (TNBC), the most heterogeneous type of breast cancer, has a high risk of recurrence and a shorter overall survival compared to the other subtypes. The ability of mitochondria to flexibly adapt to their microenvironment makes them crucial tumorigenesis mediators. in this study, we explored the role of mitochondrial dynamics in TNBC drug resistance and tumorigenesi...

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Literature Corpus work
6231433c-4c61-563e-bada-3e80f1141061
DOI
10.21203/rs.3.rs-2801568/v1
Open publication

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Targeting DRP1 mediated mitochondrial metabolism as a novel treatment strategy for triple negative breast cancer (TNBC)DOI 10.21203/rs.3.rs-2801568/v1
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