Article

Radiation-Induced Autophagy Regulates the Fibroblast Mitochondrial Stress Response and Crosstalk with Triple-Negative Breast Cancer Cells

2022-05-18

Abstract excerpt

<h4>Summary</h4> Patients with triple-negative breast cancer (TNBC) experience high recurrence rates despite current interventions, which includes radiation therapy (RT). Tumor cells thought to be involved in recurrence survive in part due to their interactions with irradiated fibroblasts following treatment. How fibroblasts metabolically respond to RT and influence the behavior of TNBC cells is poorly understood...

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Literature Corpus work: 6dd4157c-a7b1-51fb-9e31-ac854b3ca17b
DOI: 10.1101/2022.05.17.492249

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