Article
'Mendelian randomization': an approach for exploring causal relations in epidemiology.
Public health - 1 Apr 2017
Gupta V, Walia G K, Sachdeva M P
Abstract excerpt
OBJECTIVES: To assess the current status of Mendelian randomization (MR) approach in effectively influencing the observational epidemiology for examining causal relationships. METHODS: Narrative review on studies related to principle, strengths, limitations, and achievements of MR approach. RESULTS: Observational epidemiological studies have repeatedly produced several beneficiary associations which were...
Topics
- Causality
- Epidemiologic Methods
- Genetic Variation
- Genome-Wide Association Study
- Humans
- Mendelian Randomization Analysis
- Random Allocation
- Randomized Controlled Trials as Topic