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Differential Regulation of Age-Dependent Neurodegeneration and Buildup Human Phosphorylated Tau in Neurons in <em>Drosophila</em> by ATG14L, ATG6/Beclin 1 and VPS34

2024-02-20

Abstract excerpt

Neuronal cells are believed to rely on autophagy to maintain cellular homeostasis. Nevertheless, autophagy may be a therapeutic target for neurodegenerative diseases because of the role it plays in neuronal cell death. Despite Beclin 1 association with autophagy and apoptosis, the molecular mechanisms that underlie Tau-induced vesicular pathology and Tau protein aggregates in humans remain poorly understood. Here,...

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Literature Corpus work
93b122c7-91ae-56b5-ba71-2f52b5a7ddbb
DOI
10.20944/preprints202402.1046.v1
Open publication

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Differential Regulation of Age-Dependent Neurodegeneration and Buildup Human Phosphorylated Tau in Neurons in <em>Drosophila</em> by ATG14L, ATG6/Beclin 1 and VPS34DOI 10.20944/preprints202402.1046.v1
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