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Article

Dopaminergic Neuron-Specific Autophagy-Deficient Mice.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Sato Shigeto, Hattori Nobutaka

Abstract excerpt

None of the current genetic Parkinson's disease (PD) models in mouse recapitulates all features of PD. Additionally, only a few of these models develop mild dopamine (DA) neurodegeneration. And the most parsimonious explanation for the lack of DA neurodegeneration in genetic PD models is a compensatory mechanism that results from adaptive changes during development, making it hard to observe the degenerative...

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PMID: 29804260
DOI: 10.1007/7651_2018_156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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