FusionPDB: a knowledgebase of human Fusion Proteins

Abstract excerpt

<title>Abstract</title> <p>Tumorigenic functions due to the formation of fusion genes were targeted for cancer therapeutics (i.e., kinase inhibitors). However, many fusion proteins are still awaiting being targeted for therapeutics in diverse cellular working mechanisms. Due to the lack of whole fusion protein sequences and whole 3D structures of the fusion proteins, it was hard to develop novel therapeutic appro...

Topics

Open a Topic to create a Post that cites this publication.

• Antineoplastic Agents
• Gene Expression Regulation, Neoplastic
• Gene Fusion
• Peptidase Inhibition and Analysis
• Precision Medicine
• Predictive Value of Tests
• RNA and protein synthesis mechanisms
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

93abde4b-9732-566e-9d0e-ea23864dcb34

DOI

10.21203/rs.3.rs-2202839/v2