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FusionPDB: a knowledgebase of human fusion proteins

23 Oct 2023

Abstract excerpt

Tumorigenic functions due to the formation of fusion genes have been targeted for cancer therapeutics (i.e. kinase inhibitors). However, many fusion proteins involved in various cellular processes have not been studied for targeted therapeutics. This is because the lack of complete fusion protein sequences and their whole 3D structures has made it challenging to develop new therapeutic strategies. To fill these...

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PMID: 37870473
DOI: 10.1093/nar/gkad920

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