Article

Single cell expression analysis uncouples transdifferentiation and reprogramming

2018-06-20

Abstract excerpt

Many somatic cell types are plastic, having the capacity to convert into other specialized cells (transdifferentiation)( 1 ) or into induced pluripotent stem cells (iPSCs, reprogramming)( 2 ) in response to transcription factor over-expression. To explore what makes a cell plastic and whether these different cell conversion processes are coupled, we exposed bone marrow derived pre-B cells to two different transc...

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Literature Corpus work: 93a4e877-d74b-5671-8718-5ce7044be763
DOI: 10.1101/351957

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