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Article

Role of Transcription Factors in Differentiation and Reprogramming of Hematopoietic Cells

1 Jan 2011

Abstract excerpt

Differentiation of hematopoietic cells is a sequential process of cell fate decision originating from hematopoietic stem cells (HSCs), allowing multi- or oligopotent progenitors to commit to certain lineages. HSCs are cells that are able to self-renew and repopulate the marrow for the long term. They first differentiate into multipotent progenitors (MPPs), which give rise to common lymphoid progenitors (CLPs) and...

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PMID: 21720200
DOI: 10.2302/kjm.60.47

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