Article

PEX11β-mediated improvement of mitochondrial dysfunction restores behavioral defect and cellular viability in neuropathological conditions

2025-10-26

Abstract excerpt

Peroxisomal biogenesis factor 11 beta (Pex11β) is a key regulator of peroxisome proliferation, functioning in coordination with mitochondrial fission proteins. Recent human proteome co-regulation mapping has revealed a distinctive co-expression pattern between Pex11β and components of the mitochondrial respiratory chain complex at the peroxisome–mitochondria interface. In neurodegenerative disorders, such as Hunti...

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Literature Corpus work: 939b2ea5-d534-5da4-bfe9-07fabbe8d3fe
DOI: 10.1101/2025.10.24.684183

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