Article

Formoterol improves the deficits of mitochondrial homeostasis including dynamic and transport in human SH-SY5Y neuroblastoma cells induced by mitochondrial UQCRC1 mutation in human neuronal SH-SY5Y cells via a β2-adrenoreceptor activation

2023-08-21

Abstract excerpt

Formoterol, a β2-adrenergic receptor (β2AR) agonist, has been showed to support mitochondrial biogenesis in various diseases. However, its efficacy is controversial in Parkinson’s disease (PD) and its regulatory mechanism of mitochondrial homeostasis remains unclear. This study used a cell model of human reductase core protein (UQCRC1) variants in familial parkinsonism, which expressed mitochondrial dysfunction an...

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Literature Corpus work: 06bd29c9-4399-57ee-b9e6-f5e0f718ca6b
DOI: 10.21203/rs.3.rs-3264211/v1

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Formoterol improves the deficits of mitochondrial homeostasis including dynamic and transport in human SH-SY5Y neuroblastoma cells induced by mitochondrial UQCRC1 mutation in human neuronal SH-SY5Y cells via a β2-adrenoreceptor activationDOI 10.21203/rs.3.rs-3264211/v1Read

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