Article
Dysregulation of mitochondrial fusion and fission: an emerging concept in neurodegeneration.
Acta neuropathologica - 1 Feb 2006
Frank Stephan
Abstract excerpt
Mitochondrial dysfunction is increasingly being recognized as an important factor contributing to the pathogenesis of neurodegenerative disorders. However, at present, the molecular basis underlying the decline in mitochondrial function is not really understood, but recent experimental evidence has shed some light on the pivotal role of mitochondrial morphology control in this process. In particular, dysregulated...
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