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Engineered <em>Escherichia coli </em>Strains as Therapeutic Agents in Reactive Oxygen Species (ROS)-Mediated Glioblastoma Treatment: A Systematic Review of Mechanisms, Efficacy, and Challenges

2025-07-02

Abstract excerpt

Glioblastoma multiforme (GBM) remains one of the most aggressive and treatment-resistant brain tumors, characterized by a hostile microenvironment and poor prognosis. Recent advances in synthetic biology have led to the engineering of Escherichia coli (E. coli) strains as living therapeutics capable of targeting GBM via reactive oxygen species (ROS)-mediated mechanisms. This systematic review evaluates the mechani...

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Literature Corpus work
9371ca2d-0b22-591e-ab30-ae96d2d8c689
DOI
10.20944/preprints202507.0181.v1
Open publication

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Engineered <em>Escherichia coli </em>Strains as Therapeutic Agents in Reactive Oxygen Species (ROS)-Mediated Glioblastoma Treatment: A Systematic Review of Mechanisms, Efficacy, and ChallengesDOI 10.20944/preprints202507.0181.v1
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