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Microbial Systems Enhancing CAR-Based Therapies: A Synthetic Biology Paradigm for Next-Generation Cancer Immunotherapy

2025-08-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Chimeric antigen receptor (CAR)-based immunotherapies face significant translational challenges in solid tumor applications, particularly regarding manufacturing scalability, tumor targeting specificity, and antigen heterogeneity. This systematic review evaluates microbial systems as innovative platforms to address these limitations through synthetic biology-driv...

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Literature Corpus work
f864863f-1bcf-5df3-8555-635cb8aecd30
DOI
10.21203/rs.3.rs-7408618/v1
Open publication

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Microbial Systems Enhancing CAR-Based Therapies: A Synthetic Biology Paradigm for Next-Generation Cancer ImmunotherapyDOI 10.21203/rs.3.rs-7408618/v1
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