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Rapid screening of engineered microbial therapies in a 3-D multicellular model

2018-12-10

Abstract excerpt

Synthetic biology is transforming therapeutic paradigms by engineering living cells and microbes to intelligently sense and respond to diseases including inflammation 1,2 , infections 3-5 , metabolic disorders 6,7 , and cancer 8,9 . However, the ability to rapidly engineer new therapies far outpaces the throughput of animal-based testing regimes, creating a major bottleneck for clinical translation 10,11 . I...

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Literature Corpus work
7ef5be2d-a408-50bb-8ed7-b3fa7aadc251
DOI
10.1101/491159
Open publication

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Rapid screening of engineered microbial therapies in a 3-D multicellular modelDOI 10.1101/491159
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