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Genetically engineered bacterium: Principles, practices, and prospects

13 Oct 2022

Abstract excerpt

Advances in synthetic biology and the clinical application of bacteriotherapy enable the use of genetically engineered bacteria (GEB) to combat various diseases. GEB act as a small 'machine factory' in the intestine or other tissues to continuously produce heterologous proteins or molecular compounds and, thus, diagnose or cure disease or work as an adjuvant reagent for disease treatment by regulating the immune...

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PMID: 36312915
DOI: 10.3389/fmicb.2022.997587

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