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Genetically engineered bacteria as inflammatory bowel disease therapeutics

31 Aug 2024

Abstract excerpt

Inflammatory bowel disease (IBD) is a chronic and recurrent disease caused by immune response disorders that disrupt the intestinal lumen symbiotic ecosystem and dysregulate mucosal immune functions. Current therapies available for IBD primarily focus on symptom management, making early diagnosis and prompt intervention challenging. The development of genetically engineered bacteria using synthetic biology...

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Identifiers

PMID: 39628589
DOI: 10.1016/j.engmic.2024.100167

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