Article
A programmable probiotic encapsulation system enhances therapeutic delivery <i>in vivo</i>
2021-08-03
Abstract excerpt
Recent advances in therapeutic modulation of human microbiota have driven new efforts to engineer living microbial medicines using synthetic biology. However, a long-standing challenge for live bacterial therapies is balancing the high dose required to achieve robust efficacy with the potential for sepsis. Here, we developed a genetically encoded microbial encapsulation system with tunable and dynamic expression o...
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Identifiers and source
- Literature Corpus work
- 4ca574fc-7ee2-571c-9e1b-2059cbaa02b8
- DOI
- 10.1101/2021.08.03.454638