Article

Determination of Ubiquitin Fitness Landscapes Under Different Chemical Stresses in a Classroom Setting

2015-08-25

Abstract excerpt

<h4>ABSTRACT</h4> Ubiquitination is an essential post-translational regulatory process that can control protein stability, localization, and activity. Ubiquitin is essential for eukaryotic life and is highly conserved, varying in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies in S. cerevisiae indicate that ubiquitin is highly tolerant to single amino acid mutations....

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Literature Corpus work: 92f8a0b6-6cb8-5127-bdd8-d607741082e8
DOI: 10.1101/025452

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