High-throughput phenotypic profiling of gene-environment interactions by quantitative growth curve analysis in Saccharomyces cerevisiae.

Abstract excerpt

Cell-based assays are widely used in high-throughput screening to determine the effects of toxicants and drugs on their biological targets. To enable a functional genomics modeling of gene-environment interactions, quantitative assays are required both for gene expression and for the phenotypic responses to environmental challenge. To address this need, we describe an automated high-throughput methodology that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Environment
• Share to Hydrogen Peroxide
• Share to Oxidative Stress