Article

Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, K <sub>Ca</sub> 1.1, in Sinus Node Function and Arrhythmia Risk

2020-06-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> KCNMA1 encodes the α-subunit of the large-conductance Ca 2+ -activated K + channel, K Ca 1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of K Ca 1.1 are limited and KCNMA1 has not been investigated as an AF candidate gene. <h4>Methods and Results</h4> KCNMA1 sequencing in 118 patients with familial AF identifie...

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Literature Corpus work: 92e1d785-ce50-5830-a02f-e5cd52e68e76
DOI: 10.1101/2020.06.28.176495

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