Article
What can naturally occurring mutations tell us about Ca(v)1.x channel function?
Biochimica et biophysica acta - 1 Jul 2013
Stockner Thomas, Koschak Alexandra
Abstract excerpt
Voltage-gated Ca²⁺ channels allow for Ca²⁺-dependent intracellular signaling by directly mediating Ca²⁺ ion influx, by physical coupling to intracellular Ca²⁺ release channels or functional coupling to other ion channels such as Ca²⁺ activated potassium channels. L-type Ca²⁺ channels that comprise the family of Ca(v)1 channels are expressed in many electrically excitable tissues and are characterized by their...
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