Article

DNA local structure decreases mutation rates

2018-04-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Mutation rates vary across the genome. Whereas many trans factors that influence mutation rates have been identified, as have specific sequence motifs at the 1-7 bp scale, cis elements remain poorly characterized. The lack of understanding why different sequences have different mutation rates hampers our ability to identify positive selection in evolution and to identify d...

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Literature Corpus work: 92bb4870-b00f-59bd-b83e-0287f2b263a8
DOI: 10.1101/302133

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