Article

Mutation Vulnerability Characterizes Human Cancer Genes

2018-07-03

Abstract excerpt

Recent studies by Tomasetti et al. revealed that the risk disparity among different types of cancer is mainly determined by inherent patterns in DNA replication errors rather than environmental factors. In this study we reveal that inherent patterns of DNA mutations plays a similar role in cancer at the molecular level. Cancer results from stochastic DNA mutations, yet non-random patterns of cancer mutations emerg...

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Literature Corpus work: 6e885485-48ee-5e8a-885e-0a3e60d4d6c3
DOI: 10.1101/360065

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