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Article

Considering the APOE locus in Alzheimer's disease polygenic scores in the Health and Retirement Study: a longitudinal panel study.

BMC medical genomics - 3 Nov 2020

Ware Erin B, Faul Jessica D, Mitchell Colter M, Bakulski Kelly M

Abstract excerpt

BACKGROUND: Polygenic scores are a strategy to aggregate the small, additive effects of single nucleotide polymorphisms across the genome. With phenotypes like Alzheimer's disease, which have a strong and well-established genomic locus (APOE), the cumulative effect of genetic variants outside of this area has not been well established in a population-representative sample. METHODS: Here we examine the association...

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Identifiers

PMID: 33143703
DOI: 10.1186/s12920-020-00815-9
PMCID: PMC7607711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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