Article
Expressed barcodes enable clonal characterization of chemotherapeutic responses in chronic lymphocytic leukemia
2019-09-08
Abstract excerpt
The remarkable evolutionary capacity of cancer is a major challenge to current therapeutic efforts. Fueling this evolution is its vast clonal heterogeneity and ability to adapt to diverse selective pressures. Although the genetic and transcriptional mechanisms underlying these responses have been independently evaluated, the ability to couple genetic alterations present within individual clones to their respective...
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Identifiers and source
- Literature Corpus work
- 91e61fdb-b26f-551f-8874-74fb8e1dd072
- DOI
- 10.1101/761981