Article

Transcriptional signature in microglia isolated from an Alzheimer’s disease mouse model treated with scanning ultrasound

2021-12-21

Abstract excerpt

<h4>Rationale</h4> Intracranial scanning ultrasound combined with intravenously injected microbubbles (SUS +MB ) has been shown to transiently open the blood-brain barrier and reduce amyloid-β (Aβ) pathology in the APP23 mouse model of Alzheimer’s disease (AD). This has been accomplished, at least in part, through the activation of microglial cells; however, their response to the SUS treatment is only incomplete...

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Literature Corpus work: 91c3ddb4-4659-5ede-b44c-df389c09948f
DOI: 10.1101/2021.12.20.473590

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