Article
Genome-wide analysis of functional and evolutionary features of tele-enhancers.
G3 (Bethesda, Md.) - 16 Apr 2014
Huang Di, Ovcharenko Ivan
Abstract excerpt
We investigated sequence features of enhancers separated from their target gene by at least one intermediate gene/exon (named tele-enhancers in this study) and enhancers residing inside their target gene locus. In this study, we used whole genome enhancer maps and gene expression profiles to establish a large panel of tele-enhancers. By contrasting tele-enhancers to proximal enhancers targeting heart genes, we...
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