Article

The genetic status of IDH1/2 and EGFR dictates the vascular landscape and the progression of gliomas

2020-09-21

Abstract excerpt

<h4>Rationale</h4> Glioma progression is driven by the induction of vascular alterations but how the tumor genotype influence these changes is still a pending issue. We propose to study the underlying mechanisms by which the genetic changes in isocitrate dehydrogenase 1/2 ( IDH1/2 ) and epidermal growth factor receptor ( EGFR ) genes establish the different vascular profiles of gliomas. <h4>Methods</h4> We...

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Literature Corpus work: 918c9d4a-46fe-5468-9fb5-e4321f3bc10c
DOI: 10.1101/2020.09.21.306134

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