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Oncogenic drivers shape the tumor microenvironment in human gliomas

2025-05-21

Abstract excerpt

Gliomas are aggressive and heterogeneous brain tumors with limited treatment options. While oncogenic mutations in gliomas have been well-characterized, their impact on the tumor microenvironment remains poorly understood. To investigate how genomic alterations may influence the glioma microenvironment, we performed an integrative multiomic and spatial transcriptomic analysis of 93 glioma samples (46 IDH-mutant gl...

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Literature Corpus work
fc20b755-3807-551c-acfb-a65efddd6e9d
DOI
10.1101/2025.05.16.654515
Open publication

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Oncogenic drivers shape the tumor microenvironment in human gliomasDOI 10.1101/2025.05.16.654515
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