Article
Current biomarker-associated procedures of cancer modeling-a reference in the context of IDH1 mutant glioma
21 Nov 2020
Abstract excerpt
Abstract Isocitrate dehydrogenases (IDH1/2) are central molecular markers for glioblastoma. Providing in vitro or in vivo models with mutated IDH1/2 can help prepare facilities to understand the biology of these mutated genes as glioma markers, as well as help, improve therapeutic strategies. In this review, we first summarize the biology principles of IDH and its mutations and outline the core primary findings...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
