Article

The master energy homeostasis regulator PGC-1α couples transcriptional co-activation and mRNA nuclear export

2021-09-19

Abstract excerpt

PGC-1α plays a central role in maintaining the mitochondrial and energy metabolism homeostasis, linking external stimuli to the transcriptional co-activation of genes involved in adaptive and age-related pathways. The carboxyl-terminus encodes a serine/arginine-rich (RS) region and a putative RNA recognition motif, however potential RNA-processing role(s) have remained elusive for the past 20 years. Here, we show...

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Literature Corpus work: 90f3513c-2e7f-580b-aa41-97fdd6c070e5
DOI: 10.1101/2021.09.19.460961

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