Article

Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia

2021-02-10

Abstract excerpt

<h4>SUMMARY</h4> Internal ribosome entry sites (IRESs) drive translation initiation during stress. In response to hypoxia, (lymph)angiogenic factors responsible for tissue revascularization in ischemic diseases are induced by the IRES-dependent mechanism. Here we searched for IRES trans -acting factors (ITAFs) active in early hypoxia in mouse cardiomyocytes. Using knock-down and proteomics approaches, we show a...

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Literature Corpus work: 60892868-2803-51d3-8077-e5939ef21c6f
DOI: 10.1101/2021.02.10.430272

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