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Article

Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1.

The Journal of biological chemistry - 4 Jun 2010

Chang Ji Suk, Huypens Peter, Zhang Yubin, Black Chelsea, Kralli Anastasia, Gettys Thomas W

Abstract excerpt

Peroxisome proliferator-activated receptor gamma co-activator-1alpha (PGC-1alpha) plays a central role in the regulation of cellular energy metabolism and metabolic adaptation to environmental and nutritional stimuli. We recently described a novel, biologically active splice variant of PGC-1alpha (NT-PGC-1alpha, amino acids 1-270) that retains the ability to interact with and transactivate nuclear hormone...

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Identifiers

PMID: 20351112
DOI: 10.1074/jbc.M109.083121
PMCID: PMC2878565

Genes

PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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