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Article

RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensates

2020-09-23

Abstract excerpt

The peroxisome-proliferator-activated receptor-γ coactivator-1α (PGC-1α) integrates environmental cues by controlling complex transcriptional networks in various metabolically active tissues. However, it is unclear how a transcriptional coregulator coordinates dynamic biological programs in response to multifaceted stimuli such as endurance training or fasting. Here, we discovered a central function of the poorly...

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Identifiers and source

Literature Corpus work
3e00aa8d-e910-57ca-880f-da5b7d803489
DOI
10.1101/2020.09.23.310623
Open publication

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RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensatesDOI 10.1101/2020.09.23.310623
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