Article

Structural modelling of human complement FHR1 and two of its synthetic derivatives provides insight into their <i>in-vivo</i> functions

2022-11-24

Abstract excerpt

<h4>ABSTRACT</h4> Human complement is the first line of defence against invading pathogens and is involved in tissue homeostasis. Complement-targeted therapies to treat several diseases caused by a dysregulated complement are highly desirable. Despite huge efforts invested in their development, only very few are currently available, and a deeper understanding of the numerous interactions and complement regulation...

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Literature Corpus work: 90ddf56e-2f99-57b5-b44b-e3bc49d58d51
DOI: 10.1101/2022.11.24.517849

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