A Family Affair: Addressing the Challenges of Factor H and the Related Proteins

doi:10.3389/fimmu.2021.660194

Article

A Family Affair: Addressing the Challenges of Factor H and the Related Proteins

30 Mar 2021

Abstract excerpt

Inflammation is a common denominator of diseases. The complement system, an intrinsic part of the innate immune system, is a key driver of inflammation in numerous disorders. Recently, a family of proteins has been suggested to be of vital importance in conditions characterized by complement dysregulation: the human Factor H (FH) family. This group of proteins consists of FH, Factor H-like protein 1 and five...

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